Second, much of the research is thoughtless or frivolous. Efforts to engineer paler trout for better visibility in the stream, square trees for easier lumbering, and injectable scent cells so you'll always smell of your favorite perfume may seem like a joke, but they are not. Indeed, the fact that biotechnology can be applied to the industries traditionally subject to the vagaries of fashion, such as cosmetics and leisure activities, heightens concern about the whimsical use of this powerful new technology.

Third, the work is uncontrolled. No one supervises it. No federal laws regulate it. There is no coherent government policy, in America or anywhere else in the world. And because the products of biotechnology range from drugs to farm crops to artificial snow, an intelligent policy is difficult.

But most disturbing is the fact that no watchdogs are found among scientists themselves. It is remarkable that nearly every scientist in genetics research is also engaged in the commerce of biotechnology. There are no detached observers. Everybody has a stake.

The commercialization of molecular biology is the most stunning ethical event in the history of science, and it has happened with astonishing speed. For four hundred years since Galileo, science has always proceeded as a free and open inquiry into the workings of nature. Scientists have always ignored national boundaries, holding themselves above the transitory concerns of politics and even wars. Scientists have always rebelled against secrecy in research, and have even frowned on the idea of patenting their discoveries, seeing themselves as working to the benefit of all mankind. And for many generations, the discoveries of scientists did indeed have a peculiarly selfless quality.

When, in 1953, two young researchers in England, James Watson and Francis Crick, deciphered the structure of DNA, their work was bailed as a triumph of the human spirit, of the centuries-old quest to understand the universe in a scientific way. It was confidently expected that their discovery would be selflessly extended to the greater benefit of mankind.